Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)

Inactive on SAM.gov — responses were due 9 Oct 2026 · Unrestricted (full and open) · Defense Advanced Research Projects Agency (DARPA), DoD · NAICS 541715 · Solicitation DARPA-PA-25-07-06

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SAM.gov marked this notice inactive — responses were due 09 October 2026.

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Solicitation details

Solicitation number	DARPA-PA-25-07-06
Notice ID	3ac25ac710fb438e8d25d99783cee845
Agency	Department of Defense (DoD)
Sub-agency	Defense Advanced Research Projects Agency (DARPA)
Contracting office	DEF ADVANCED RESEARCH PROJECTS AGCY
NAICS code	541715 — Research and Development in the Physical, Engineering, and Life Sciences (Except Nanotechnology and Biotechnology)
Product / service code (PSC)	AC11
Set-aside	Unrestricted (full and open)
Notice type	Solicitation
Posted	03 September 2026
Response deadline	09 October 2026 (closed)
Competition	Competitive

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Description

The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is issuing a Disruption Opportunity (DO), inviting submissions of innovative basic or applied research concepts in the technical domain of targeted neuroplasticity. This DO is issued under the Program Announcement for Disruptioneering, DARPA-PA-25-07 Amendment 1. All awards will be made in the form of an Other Transaction (OT) for Prototype Agreement. The total award value for this DO is limited to $2,000,000 per award. This total award value includes Government funding and performer cost share if required or proposed.

Version history

SAM.gov has posted 3 notices under solicitation DARPA-PA-25-07-06, oldest first.

28 August 2026 — Solicitation
03 September 2026 — Solicitation (this page)
28 September 2026 — Solicitation (latest)

Documents in the solicitation package

6 files are attached to this notice.

DARPA-PA-25-07-06-Amendment-01.pdf
SHINE_Amendment_1_Summary_of_Changes.docx
SHINE_Streamlined_Cost_Buildup_Workbook_Amendment_1.xlsx
DARPA-PA-25-07-06.pdf
Streamlined_Cost_Buildup_Workbook.xlsx
Original Solication: DARPA-PA-25-07 - Disruptioneering Program Announcement

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Market context: DoD and NAICS 541715

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