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Non-Optical Methods for High Speed Protein Control

Open — responses due 31 Dec 2026 (55 days left) · Unrestricted (full and open) · Defense Advanced Research Projects Agency (DARPA), DoD · NAICS 541714 · Solicitation DARPA-SN-26-89

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A newer version of this notice has been posted. SAM.gov republished solicitation DARPA-SN-26-89 on 21 July 2026. This page is kept because it is a real record, but the current requirement, dates and attachments are on the latest version. Read the latest version →

Solicitation details

Solicitation numberDARPA-SN-26-89
Notice ID406c91d063494363aee2746d5fe476df
AgencyDepartment of Defense (DoD)
Sub-agencyDefense Advanced Research Projects Agency (DARPA)
Contracting officeDEF ADVANCED RESEARCH PROJECTS AGCY
NAICS code541714 — Research and Development in Biotechnology (Except Nanobiotechnology)
Product / service code (PSC)AC12
Set-asideUnrestricted (full and open)
Notice typeSpecial Notice
Posted21 July 2026
Response deadline31 December 2026
CompetitionCompetitive

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Description

UPDATE: The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

Version history

SAM.gov has posted 3 notices under solicitation DARPA-SN-26-89, oldest first.

Documents in the solicitation package

2 files are attached to this notice.

  • DARPA-SN-26-89-Amendment-01.pdf
  • DARPA-SN-26-89.pdf

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Market context: DoD and NAICS 541714

About the buyer and the industry, not this specific solicitation. Source: USASpending.gov award data, updated nightly.

  • In fiscal year 2026, DoD obligated $97.1M across 47 contract actions under NAICS 541714.
  • 74 contracts worth $355.7M in this category end within the next 18 months.

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