IDENTIFY Study Participants 5-Base Sample Preparation and Whole Genome Multiomic Profiling

Inactive on SAM.gov — responses were due 15 Sep 2026 · No Set aside used · National Institutes of Health (NIH), HHS · Bethesda, MD · NAICS 541380 · Solicitation 75N98026Q01158

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SAM.gov marked this notice inactive — responses were due 15 September 2026.

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Solicitation details

Solicitation number	75N98026Q01158
Notice ID	8ef56e0d7638449d8edbd1f9670cd4d1
Agency	Department of Health and Human Services (HHS)
Sub-agency	National Institutes of Health (NIH)
Contracting office	NATIONAL INSTITUTES OF HEALTH
NAICS code	541380 — Testing Laboratories and Services
Set-aside	No Set aside used
Notice type	Special Notice
Posted	08 September 2026
Response deadline	15 September 2026 (closed)
Place of performance	Bethesda, MD, USA

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Description

The Prenatal Genomics and Therapy Section (PGTS), Center for Precision Health Research (CPHR), National Human Genome Research Institute (NHGRI), requires 5-base whole genome sequencing services for stored plasma-derived cell-free DNA samples collected under the IDENTIFY study. These samples were obtained from women who received prenatal cell-free DNA sequencing results suggestive of maternal malignancy. 5Base sample prep and whole genome multiomic profiling at 30x is required to generate high-resolution genomic and epigenomic data suitable for tissue-of-origin analyses. The objective of this acquisition is to obtain high-quality, comprehensive 5-base sequencing data that will support the development and refinement of computational models to determine the tissue source of incidentally detected maternal cancers. The resulting data will be incorporated into ongoing bioinformatic and translational research efforts within PGTS to improve interpretation of prenatal cell-free DNA sequencing results, enhance early cancer detection strategies in pregnancy, and advance understanding of circulating cell-free DNA biology in the context of malignancy.

Documents in the solicitation package

1 file is attached to this notice.

BROAD_NonComp Posting_NHGRI_AM.doc

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Market context: HHS and NAICS 541380

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In fiscal year 2026, HHS obligated $48.5M across 105 contract actions under NAICS 541380.
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