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IDENTIFY Study Participants 5-Base Sample Preparation and Whole Genome Multiomic Profiling

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · Solicitation 75N98026Q01158 · NAICS 541380 · No Set aside used · Responses due 15 September 2026

Solicitation details

Solicitation number75N98026Q01158
Notice ID8ef56e0d7638449d8edbd1f9670cd4d1
AgencyHEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tierNATIONAL INSTITUTES OF HEALTH
Contracting officeNATIONAL INSTITUTES OF HEALTH
NAICS code541380
Set-asideNo Set aside used
Notice typeSpecial Notice
Posted08 September 2026
Response deadline15 September 2026
Place of performanceBethesda, MD, USA

Description

The Prenatal Genomics and Therapy Section (PGTS), Center for Precision Health Research (CPHR), National Human Genome Research Institute (NHGRI), requires 5-base whole genome sequencing services for stored plasma-derived cell-free DNA samples collected under the IDENTIFY study. These samples were obtained from women who received prenatal cell-free DNA sequencing results suggestive of maternal malignancy. 5Base sample prep and whole genome multiomic profiling at 30x is required to generate high-resolution genomic and epigenomic data suitable for tissue-of-origin analyses. The objective of this acquisition is to obtain high-quality, comprehensive 5-base sequencing data that will support the development and refinement of computational models to determine the tissue source of incidentally detected maternal cancers. The resulting data will be incorporated into ongoing bioinformatic and translational research efforts within PGTS to improve interpretation of prenatal cell-free DNA sequencing results, enhance early cancer detection strategies in pregnancy, and advance understanding of circulating cell-free DNA biology in the context of malignancy.

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