Intelligent Generator of Research (IGoR) - ISO

Inactive on SAM.gov — responses were due 13 Aug 2026 · No Set aside used · National Institutes of Health (NIH), HHS · NAICS 541715 · Solicitation ARPA-H-SOL-26-155

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SAM.gov marked this notice inactive — responses were due 13 August 2026.

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Solicitation details

Solicitation number	ARPA-H-SOL-26-155
Notice ID	a22fc1e7ee8f46c79e8adf9b560d8a74
Agency	Department of Health and Human Services (HHS)
Sub-agency	National Institutes of Health (NIH)
Contracting office	ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
NAICS code	541715 — Research and Development in the Physical, Engineering, and Life Sciences (Except Nanotechnology and Biotechnology)
Product / service code (PSC)	AN13
Set-aside	No Set aside used
Notice type	Solicitation
Posted	28 July 2026
Response deadline	13 August 2026 (closed)

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Description

Amendment 03 provides revisions to Appendix C_Proposal Format and Intructions, as highlighted in yellow. This amendment also provides revisions to Appendix C.4_Price Proposal Spreadsheet (removes phase durations on labor tab). --------------------------------------------------------------------------------------- Amendment 02 extends the proposal due date and provides revisions to Appendix A_Program and Technical Description and Appendix E_Draft Model OT Agreement, as highlighted in yellow. --------------------------------------------------------------------------------------- Amendment 01 adds Appendix E_Draft Model OT Agreement and provides revisions to Appendix B_Solution Summary Format and Instructions, as highlighted. --------------------------------------------------------------------------------------- ARPA-H intends to host a hybrid Proposers Day in early June in the Washington, D.C. metro area. Additional information will be posted when it becomes availiable. The Intelligent Generator of Research (IGoR) program aims to eliminate longstanding inefficiencies in research and accelerate the development of effective therapies for complex diseases by creating an AI-enabled interoperable research ecosystem. IGoR would develop: 1) mechanistic disease models that encode causal biological relationships across scales, 2) an AI orchestration layer that identifies knowledge gaps and designs optimal experiments, 3) a layered protocol architecture that enables any qualified laboratory to execute the same experiment reproducibly, and 4) a distributed marketplace of validated laboratories that execute standardized protocols and return gold-standard data. Together, these components form a cycle of hypothesis generation, experimentation, and model refinement that enables researchers to create validated knowledge at least 10x more rapidly than conventional approaches. Ultimately, IGoR will empower researchers at every level to pursue bold, unconventional research directions that are currently too slow, too complex, or too resource?intensive.

Version history

SAM.gov has posted 4 notices under solicitation ARPA-H-SOL-26-155, oldest first.

05 May 2026 — Solicitation
26 May 2026 — Solicitation
08 July 2026 — Solicitation
28 July 2026 — Solicitation (this page)

Documents in the solicitation package

11 files are attached to this notice.

IGoR ISO OT_ARPA-H-SOL-26-155_Amendment 02.pdf
APPENDIX A_Program and Technical Description_IGoR_Amendment 02.pdf
APPENDIX B_Solution Summary Format and Instructions_IGoR_Admendment 01.docx
APPENDIX C_Proposal Format and Instructions_IGoR_Amendment 03.pdf
APPENDIX C.1_Technical and Management Proposal_IGoR.docx
APPENDIX C.2_Task Description Document_IGoR.docx
APPENDIX C.3_Price Proposal_IGoR.docx
APPENDIX C.4_Price Proposal Spreadhsheet_IGoR_Amendment 03.xlsx
APPENDIX D_Admin National Policy Document_IGoR.docx
APPENDIX E_Draft Model OT Agreement_IGoR_Amendment 02.docx
IGoR Program Website

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Market context: HHS and NAICS 541715

About the buyer and the industry, not this specific solicitation. Source: USASpending.gov award data, updated nightly.

In fiscal year 2026, HHS obligated $406.8M across 212 contract actions under NAICS 541715.
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