Solicitations › HEALTH AND HUMAN SERVICES, DEPARTMENT OF › NAICS 325414

Whole Exome Analysis of NIAAA Clinical Center pATIENTS

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · Solicitation 75N98026Q00677 · NAICS 325414 · No Set aside used · Closed

Solicitation details

Solicitation number	75N98026Q00677
Notice ID	aa04d360a0034c6cbe4e2bae2a6f17c2
Agency	HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier	NATIONAL INSTITUTES OF HEALTH
Contracting office	NATIONAL INSTITUTES OF HEALTH OLAO
NAICS code	325414
Product / service code (PSC)	6505
Set-aside	No Set aside used
Notice type	Presolicitation
Posted	22 June 2026
Response deadline	02 July 2026 (closed)
Place of performance	Bethesda, MD, USA
Competition	Competitive

Description

The NIAAA Clinical Center patient cohort has been analyzed patients for sequence variant differences, and changes in response to treatment over the course of many years as part of an effort to identify underlying causes of alcohol related disorders. Analysis has previously been performed on over 2000 patients using the AmpliSeq Exome enrichment system and sequenced on the ION sequencing platform because it provides the capability of cost-effective high throughput whole-exome genome-wide analysis. The use of a single enrichment and sequencing platform with consistent information content is essential for analysis of samples screened at different times and it is therefore imperative for analytical integrity that all samples in the study are processed on the same sequencing platform, as each platform has a unique pattern of error

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