Chemical Security Analysis Center (CSAC) Rapid Cyanide Detection RFI
Inactive on SAM.gov — responses were due 2 Sep 2026 · Unrestricted (full and open) · Office of Procurement Operations, DHS · Solicitation 70RSAT26RFI000021
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SAM.gov marked this notice inactive — responses were due 02 September 2026.
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This Request for Information (RFI) supports the Department of Homeland Security (DHS) Science and Technology (S&T) Directorate s efforts to conduct market research in support of the Chemical Security Analysis Center (CSAC). DHS S&T is tasked with researching and organizing the scientific, engineering, and technological resources of the United States and leveraging these existing resources into technological tools to help protect the homeland. S&T Chemical Security Analysis Center (CSAC) is the only federal studies, analysis, and knowledge management center for assessing critical chemical dependencies, emerging threats and technologies, and accidental or intentional chemical events in the United States. CSAC supports the homeland security community by providing a crucial knowledge repository of chemical threat information, design and execution of laboratory and field tests, and a science-based threat and risk analysis capability, among other services. DHS has patented a human biomarker system and method for cyanide exposure detection. In order to advance the patented technology, S&T CSAC is looking to enter into a Cooperative Research and Development Agreement (CRADA) with relevant collaborator(s) to inform a development pathway for its cyanide exposure detection system. This collaboration will expand interaction with industry to ensure that first responders and the American public are afforded access to state-of-the-art detection technology solutions that save lives. The objective of this RFI is to gather detailed insights from companies and consortia engaged in the engineering, testing, and manufacturing of medical device prototypes relevant to the detection of human cyanide exposure. DHS seek collaborator(s) with expertise in chemical medical countermeasures, particularly those that can demonstrate a robust background in developing detection technologies for hazardous substances, including past projects and relevant experience. Responses should outline the engineering and design processes utilized in creating prototypes, including biomarker selection and validation methodologies, as well as comprehensive cost estimates and timelines for development from proof of concept through regulatory approval and manufacturing. Additionally, respondents should provide information on navigating the regulatory landscape for medical devices, including experience with agencies like the Food and Drug Administration (FDA), and detail their manufacturing capabilities, including scalability and compliance with industry standards.
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