Biosequence Search

Open — responses due 17 Nov 2026 (3 days left) · No Set aside used · U.S. Patent and Trademark Office, DOC · Alexandria, VA · NAICS 518210 · Solicitation ACQ-27-0065

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Solicitation details

Solicitation numberACQ-27-0065
Notice IDfb420b2657194bfdb668ba02d6531f25
AgencyDepartment of Commerce (DOC)
Sub-agencyU.S. Patent and Trademark Office
Contracting officeDEPT OF COMMERCE PTO
NAICS code518210 — Data Processing, Hosting, and Related Services
Product / service code (PSC)DH10
Set-asideNo Set aside used
Notice typeSources Sought
Posted04 November 2026
Response deadline17 November 2026
Place of performanceAlexandria, VA, USA
CompetitionCompetitive

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Description

The United States Patent and Trademark Office (USPTO) is conducting market research through this Request for Information (RFI) to gather input from industry on commercially available solutions to search biological sequences, such as DNA, RNA, proteins, peptides, antibodies, probes, primers, fragments, variants, and fusion constructs, as well as prior art searches, claimed in patent applications. The USPTO seeks innovative solutions to implement the next-generation biological sequence search system utilizing Super Intelligence (SI)-assisted capabilities to increase the efficiency and quality of biological searches during patent examinations. The USPTO is interested in solutions that meet the objectives outlined in the attached draft Statement of Objectives (SOO). The Government preference is to obtain a turnkey commercial solution with minor tailoring, if applicable. The Government contemplates utilizing the Alternative Competition Method in accordance with the Patent and Trademark Office Acquisition Guidelines (PTAG) and the Patent and Trademark Office Efficiency Act 35 U.S.C. § 2(b)(4)(A). This PTAG Request for Information (RFI) is intended as preliminary market information gathering which the USPTO will use to determine which vendor(s) is/are the most likely to successfully meet the agency’s needs and are thereby eligible to participate in an alternative competition. As a result of this market research, the solicitation will only be issued to the limited number of qualified vendor(s). Vendors that do not respond to the RFI will not be considered for the alternative competition and will not be eligible to compete as a prime offeror. Submission of an RFI response does not guarantee a vendor’s eligibility to compete for the biosequence search requirement. This PTAG RFI is not a request for competitive proposals. This RFI is not a solicitation and does not constitute a request for quotations or proposals. The USPTO is not seeking or accepting unsolicited proposals. There is no USPTO commitment or implied agreement or understanding as a result of Government action or inaction taken in response to the RFI or the accompanying documents. Telephone calls requesting a solicitation will not be accepted or acknowledged. Participation in this effort is strictly voluntary. No entitlement to payment will arise as a result of submission of a response to the RFI. Any cost for submission of responses or associated activities is at the interested respondent’s risk and interested respondent’s expense. The USPTO is not liable for costs (direct or indirect) associated with the preparation, submission, or responses to this RFI, including any costs associated with any meetings, follow on questions or additional requests for information, if any. USPTO will not reimburse the respondent for any costs incurred in responding to the RFI. See the attached "ACQ-27-0065 - RFI Biosequence Tool" for submission instructions.

Documents in the solicitation package

8 files are attached to this notice.

  • RFI Attachment 2 - Biosequence Search SOO.pdf
  • ACQ-27-0065 - RFI Biosequence Tool.pdf
  • RFI Attachment 3 - Question and Answer Sheet.xlsx
  • RFI Attachment 1 - RFI Response Template_v0.1.xlsx
  • Appendix D.docx
  • Appendix C.docx
  • Appendix B.docx
  • Appendix A.docx

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Market context: DOC and NAICS 518210

About the buyer and the industry, not this specific solicitation. Source: USASpending.gov award data, updated nightly.

  • In fiscal year 2026, DOC obligated $61.5M across 34 contract actions under NAICS 518210.
  • 39 contracts worth $330.4M in this category end within the next 18 months.

DOC contracts under NAICS 518210 →

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Source: this notice on SAM.gov. FedSift republishes public federal procurement data and is not affiliated with the U.S. Government. Always confirm dates and requirements against SAM.gov before responding.

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