Chromatin immunoprecipitation sequencing laboratory services for genetic material binding analysis in mouse stem cells

General Information Document Type: Presolicitation Synopsis Number: 75N98026Q01153 Posted Date: September 8, 2026 Original Response Date: September 18, 2026 Current Response Date: September 18, 2026 Set Aside: N/A NAICS Code: 811210 Contracting Office Address National Institutes of Health (NIH), Office of the Director (OD) Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM) Hospital and Laboratory Support Division 6701 Rockledge Drive Bethesda, MD 20817 Description INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health (NIH) intends to negotiate and award a contract without providing for full and open competition (Including brand-name) to: Active Motif 1914 Palomar Oaks Way Suite 150 Carlsbad, California 92008 NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 811210 with a Size Standard $1000. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01, March 13, 2026. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($350,000). STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source and is not expected to exceed the simplified acquisition threshold. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. GENERAL INFORMATION Title: Chromatin immunoprecipitation sequencing laboratory services for genetic material binding analysis in mouse stem cells Background Information: The National Institute of Diabetes and Digestive and Kidney Diseases is conducting research to better understand how the EXOSC10 protein contributes to genome stability during the repair of deoxyribonucleic acid damage. To support this research, the laboratory developed a mouse embryonic stem cell line in which the EXOSC10 protein contains a three-times FLAG tag, allowing the protein to be detected and enriched using an anti-FLAG antibody. Because the genome-wide binding pattern of EXOSC10 has not been fully characterized, antibody qualification is required before conducting chromatin immunoprecipitation sequencing. Matched control cell lines expressing green fluorescent protein with the same three-times FLAG tag will be used to distinguish specific EXOSC10 binding from background signal and ensure reliable experimental results.. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include a technical proposal, a cost-price proposal, the period of performance, the Unique Entity ID (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by September 18, 2026 at 9:00 AM Eastern time and must reference solicitation number 75N98026Q01153. Responses may be submitted electronically to Mr. James Law, Contracting Officer at James.Law@nih.gov. Fax responses will not be accepted. "All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.