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HEALTH AND HUMAN SERVICES, DEPARTMENT OF · Solicitation 75N98026Q00800 · NAICS 541380 · No Set aside used · Closed

Solicitation details

Solicitation number	75N98026Q00800
Notice ID	0bcdbebf6ffc4be299a63e6ac5baa36f
Agency	HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier	NATIONAL INSTITUTES OF HEALTH
Contracting office	NATIONAL INSTITUTES OF HEALTH OLAO
NAICS code	541380
Product / service code (PSC)	Q301
Set-aside	No Set aside used
Notice type	Solicitation
Posted	15 July 2026
Response deadline	25 July 2026 (closed)
Place of performance	Bethesda, MD, USA
Competition	Competitive

Description

Requirements: 2.0 BACKGROUND Our lab studies the role of inflammation/innate resistance and commensal microbiota in carcinogenesis, cancer progression and therapy of cancer. The following product features/characteristics are required for this requirement: Protein Coverage - Measures ~5,400+ human proteins simultaneously in a single workflow. Technology - Uses Proximity Extension Assay (PEA) with dual antibody recognition coupled to DNA barcoding and next-generation sequencing (NGS) readout. Sample input requires only 2 ul of plasma, serum, and other sample types Specificity - Reported 99.5% specificity with negligible cross-reactivity due to dual-recognition antibody design. Dynamic Range - Approximately 10 orders of magnitude (fg/mL to mg/mL), enabling detection of both low- and high-abundance proteins. Key strengths Very broad proteome coverage while maintaining antibody-based specificity. Excellent sensitivity for low-abundance circulating proteins (especially cytokines and signaling proteins). Extremely low sample-volume requirement. Highly standardized platform, making it attractive for epidemiology and multi-omics studies.

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