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Illumina DRAGEN Tier 3 Throughput License and v4 Server

Inactive on SAM.gov — responses were due 11 Sep 2026 · No Set aside used · National Institutes of Health (NIH), HHS · Bethesda, MD · NAICS 541715 · Solicitation 75N98026Q01167

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A newer version of this notice has been posted. SAM.gov republished solicitation 75N98026Q01167 on 10 September 2026. This page is kept because it is a real record, but the current requirement, dates and attachments are on the latest version. Read the latest version →

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SAM.gov marked this notice inactive — responses were due 11 September 2026.

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Solicitation details

Solicitation number75N98026Q01167
Notice ID6b98c12f393e4bff977b9287862a1355
AgencyDepartment of Health and Human Services (HHS)
Sub-agencyNational Institutes of Health (NIH)
Contracting officeNATIONAL INSTITUTES OF HEALTH NLM
NAICS code541715 — Research and Development in the Physical, Engineering, and Life Sciences (Except Nanotechnology and Biotechnology)
Product / service code (PSC)AJ12
Set-asideNo Set aside used
Notice typeCombined Synopsis/Solicitation
Posted09 September 2026
Response deadline11 September 2026 (closed)
Place of performanceBethesda, MD, USA

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Description

The NHGRI Undiagnosed Diseases Program (UDP) requires both the Illumina DRAGEN 500,000Gb annual throughput license and the Illumina DRAGEN Server v4 to maintain secure, compliant, and high performance secondary analysis of next generation sequencing (NGS) data. DRAGEN serves as an essential computational supplement when UDP s sequencing workload exceeds CIT High Performance Computing Center allocations, enabling timely processing of whole genome, whole exome, and transcriptome datasets for patients with rare and unresolved diseases. The current DRAGEN server, procured in 2017, has reached end of support. Its CentOS 7 operating system lost vendor support and security updates on June 30, 2024, increasing operational risk. In addition, the legacy dual Intel Xeon processors, 512 Gb RAM, and first generation FPGA acceleration hardware cannot support updated DRAGEN pipelines, including pangenome references and improved germline/somatic variant calling workflows. These limitations reduce analytical accuracy, throughput, and system stability. To prevent analysis delays, maintain compliance with NIH IT security requirements, and sustain mission critical genomic interpretation capacity, the UDP must acquire both the updated throughput license and the next generation DRAGEN Server v4.

Version history

SAM.gov has posted 3 notices under solicitation 75N98026Q01167, oldest first.

Documents in the solicitation package

3 files are attached to this notice.

  • PRICING Template-rev.pdf
  • RFO 12.202(b)(1)_Combined Synopsis-Solicitation Notice.pdf
  • DRAGEN_Combined_SOW.pdf

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Market context: HHS and NAICS 541715

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  • In fiscal year 2026, HHS obligated $406.8M across 212 contract actions under NAICS 541715.
  • 319 contracts worth $3.8B in this category end within the next 18 months.

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