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Solicitations › Department of Health and Human Services › National Institutes of Health

The Therapeutic Role of Soluble Adenylyl Cyclase Inhibition in Ameliorating Inflammatory Vascular Remodeling in Pulmonary Arterial Hypertension

Closed — responses were due 21 Sep 2026 · Unrestricted (full and open) · National Institutes of Health (NIH), HHS · Chicago, IL · NAICS 541715 · Solicitation 75N98026R00085

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Solicitation details

Solicitation number75N98026R00085
Notice ID955c40f8d97c42e081a4c82c09bdb80c
AgencyDepartment of Health and Human Services (HHS)
Sub-agencyNational Institutes of Health (NIH)
Contracting officeNATIONAL INSTITUTE OF HEALTH NIH-OD
NAICS code541715 — Research and Development in the Physical, Engineering, and Life Sciences (Except Nanotechnology and Biotechnology)
Product / service code (PSC)AN12
Set-asideUnrestricted (full and open)
Notice typeSpecial Notice
Posted13 September 2026
Response deadline21 September 2026 (closed)
Place of performanceChicago, IL, USA

Description

The National Institutes of Health (NIH) intends to negotiate on a sole-source basis with the University of Illinois at Chicago (UIC) for preclinical animal research services to evaluate the therapeutic effects of soluble adenylyl cyclase (sAC) inhibition on pulmonary arterial hypertension (PAH) using an established endothelial cell-specific Cav1 knockout (EC-Cav1 KO) murine model and corresponding wild-type controls. The Government intends to solicit from a single source pursuant to FAR 13.106-1(b)(1). UIC currently maintains the established EC-Cav1 KO mouse colony required for this study, and the model is not known to be maintained by another laboratory. This notice of intent is not a request for competitive quotations. However, all responsible sources that believe they can satisfy the Government's requirements may submit a capability statement and/or quotation for consideration by the Government. Please see the attached Notice of Intent to Sole Source for the complete description of the requirement, basis for the intended sole-source acquisition, response instructions, and applicable response deadline.

Version history

SAM.gov has posted 2 notices under solicitation 75N98026R00085, oldest first.

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